Installshield Engine

[Phrostie]

I've been having trouble on newer builds of win32 applications.
I can install/run the older 2000 version with no problem but not the
2001.
when i try to install the softawre it never makes it past the install
shield.
i get the error:

The InstallShield Engine (iKernel.exe) could not be launched. 
(0x80070005)

in the console it reads:

[winead at atlanta icad2001]$ wine Setup.exe
Could not stat /mnt/fd0 (No such file or directory), ignoring drive A:
Could not stat /cdrom (No such file or directory), ignoring drive D:
fixme:ole:CoSetState (0x653c79b0),stub!
fixme:pthread_kill_other_threads_np
fixme:pthread_kill_other_threads_np
Could not stat /mnt/fd0 (No such file or directory), ignoring drive A:
Could not stat /cdrom (No such file or directory), ignoring drive D:
fixme:ole:CoSetState (0x653c79b0),stub!
fixme:ole:MkParseDisplayName (0x40426c64, L"StdOle32.tlb", 0x40636634,
0x46000000): stub.
fixme:ole:CoTreatAsClass (0x46c858,0x46e128), stub!
fixme:ole:CoSetState ((nil)),stub!
fixme:ole:CoGetClassObject CLSCTX_LOCAL_SERVER  not supported!
fixme:ole:CoCreateInstance no instance created for
{91814ebf-b5f0-11d2-80b9-00104b1f6cea}, hres is 0x80070005

I'm running mdk 8.0 and a "Wine release 20010731"

any help would be appreciated.