[Wine] CRM Commercial soft and windows authenticaction

[Pluggin]

We have a crm aplication running on windows desktops and we want to
migrate it to linux desktop. For this issue we run the apps with wine
but the problem is the aplicaction validate login users automaticaly
with our windows domain controlers. Because this fail to start...
My question is:
Running this apps using WINE could interact with  SAMBA for windows
authentication  too (challenge/response)?

Regards