[Wine] Can Wine run on anything other than x86 ?

[Anurag Mishra]

I was just reading this article
http://blog.sillica.com/2008/05/30/valve-source-engine-to-hit-linux-soon/

and author suggests that one of the Wine derivative has been used on
PS2 in order to run the DirectX features using OpenGL.
Is it technically possible to do with Wine? For all I know, Wine
waited a long to get to Mac and port was only successful after Apple
started using Intel CPU's.