[Wine] Installing games on a portable harddrive using wine

[Dalandros]

Hello I'm Chris aka Dalandros, this is my first post *bows* nice to meet you all ^__^

my question is if there's a possibility to install games for example "Jedi knight 2 jedi outcast" on a portable harddrive connected in the usb to the computer, instead of putting it on the harddrive. if so how is this task done?

the reason i'm asking is since i have a eeepc 700-model (i think, or was it 701? anyway..) and i just recently got eeebuntu & wine installed on it along with spotify thanks to wine! :D 
but eeepc's aren't famous for their space, thats why i'm asking.
all help is appreciated!
// Chris aka Dalandros