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[root at me Desktop]# cd /home/me/Desktop/
[root at me Desktop]# ll
total 496
-rw-r--r-- 1 me mygroup 491768 2008-03-20 14:49 ie6setup.exe
drwxr-xr-x 7     501      501   4096 2007-11-26 06:28 ies4linux-2.99.0.1
-rw-r--r-- 1 me mygroup   197 2008-03-13 16:35 OpenOffice.desktop
[root at me Desktop]# wine ie6setup.exe
fixme:advapi:CheckTokenMembership ((nil) 0x11d9c8 0x32fd78) stub!
fixme:advapi:DecryptFileA "C:\\windows\\temp\\IXP000.TMP\\" 00000000
Application tried to create a window, but no driver could be loaded.
Unknown error (998).
Application tried to create a window, but no driver could be loaded.
Unknown error (998).
err:ole:apartment_createwindowifneeded CreateWindow failed with error 0
fixme:cursor:CURSORICON_LoadFromFile No support for .ani cursors.
fixme:advpack:set_ldids Need to support changing paths - default will be used
fixme:advpack:set_ldids Need to support changing paths - default will be used
fixme:advpack:NeedReboot (0): stub
[root at me Desktop]#


I should note that i have done a yum update on wine.

Apologies if this is a little vague, please let me know if there is any more information i can get to make it more clear.

Cheers
Brian